Luca Coscioni’s greatest passion was running marathons until he was diagnosed with amyotrophic lateral sclerosis. Soon in need of a change in career, he became the leader of the Italian Radical Party. Once in position he struggled for the freedom of scientific research. This documentary presents the evolution of his disease, his everyday life, his battle, his appeals to the European Parliament, the meetings with scientists. The topical subjects of freedom for scientific research and therapeutic cloning bring Luca into deep reflections on ethics, religion, hope and the sense of his own life.