In 1967 Canadian filmmaker Hugh O'Connor visited the mountains of Central Appalachia in eastern Kentucky, to document poverty. A local landlord, who resented the presence of filmmakers on his property, shot and killed O'Connor, in part because of his anger over the media images of Appalachia that had become icons in the nation's War on Poverty. The filmmaker, a native of Appalachia, uses O'Connor's death as a lens to explore the complex relationship between those who make films to promote social change and the people whose lives are represented in such media productions. Through first-person accounts of the killing and the perspective of three decades of reflection, “Stranger with a Camera” leads viewers on a quest for understanding - a quest that ultimately leads the filmmaker to examine her own role as both a maker of media and a member of the Appalachian community she portrays.